Across

• 1.

  NEIL ARMSTRONG (Mr. Alien rev. + strong), MOON MULLINS
• 11.

  ERIE (hidden)
• 12.

  CARDINAL (double def.)
• 14.

  TUNNEL (anag.)
• 15.

  ELBOW
• 16.

  WHISTLER (anag. + w), TWEETIE
• 18.

  SO(methi)NG
• 19.

  FIRST (first letters)
• 21.

  FRANC-IS BACON, PORKY PIG
• 25.

  O-BE-Y
• 28.

  MAT-UR-ER (mater around our "but [for the] first")
• 30.

  A-LB-UM
• 33.

  SP-IRE
• 34.

  ATLAS (double def.)
• 35.

  EDGE (double def.)
• 37.

  FRAGMENTS (anag.)
• 40.

  COURTED (true anag. in cod)
• 41.

  WADDLE (re-headed saddle)
• 42.

  FAME (hidden)
• 43.

  WHITE-HEAD, BLONDIE
• 44.

  FIN-ALE
• 45.

  MI(T)RE
• 46.

  SIR FRANCIS DRAKE (anag.), DONALD DUCK

Down

• 1.

  CHECKERS (double def.), MUTT
• 2.

  ORNERY (hidden)
• 3.

  NINES (double def.)
• 4.

  MEET (double def.)
• 5.

  LAZE (homophone)
• 6.

  IDLE (anag.)
• 7.

  NIBS (double def.)
• 8.

  MATA HARI (anag.), SNOOPY
• 9.

  FAWN (double def.)
• 10.

  MARCIANO (anag.), SLUGGO
• 12.

  CLIPPER (double def.)
• 13.

  RETRO (terro[rists] anag.)
• 17.

  FREUD (fraud with "change of heart"), WIZARD OF ID
• 19.

  FE(MM)E
• 20.

  TH-RIFT
• 22.

  YELL (with ow is "cowardly")
• 23.

  NIETZSCHE (anag.), SUPERMAN
• 24.

  TREAD-LED
• 26.

  BABE RUTH, BATMAN
• 27.

  HUSTLERS (anag.)
• 29.

  EARL OF SANDWICH (anag.), DAGWOOD
• 31.

  BANDIT (homophonic pun)
• 32.

  MOS-EYED
• 36.

  GUANO (hidden rev.)
• 38.

  REBEL (re instead of la on "label")
• 39.

  EDDIC (hidden)
• 40.

  CA-FE